Differential Macrophage Responses in Affective Versus Non-Affective First-Episode Psychosis Patients
نویسندگان
چکیده
منابع مشابه
Grey matter abnormalities in first-episode schizophrenia and affective psychosis.
BACKGROUND Grey matter and other structural brain abnormalities are consistently reported in first-onset schizophrenia, but less is known about the extent of neuroanatomical changes in first-onset affective psychosis. AIMS To determine which brain abnormalities are specific to (a) schizophrenia and (b) affective psychosis. METHOD We obtained dual-echo (proton density/T2-weighted) magnetic r...
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A high prevalence of abnormal cavum septi pellucidi (CSP) in schizophrenia may reflect neurodevelopmental abnormalities in midline structures of the brain. The relationship, however, between abnormal CSP and clinical symptoms, and with abnormalities in other limbic structures remains unclear, as does the question of whether a similar abnormality is present in affective psychosis. Seventy-four p...
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BACKGROUND Reviews conclude that childhood and adolescence sexual, physical, emotional abuse and emotional and physical neglect are all risk factors for psychosis. However, studies suggest only some adversities are associated with psychosis. Dose-response effects of several adversities on risk of psychosis have not been consistently found. The current study aimed to explore adversity specificit...
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BACKGROUND The critical period hypothesis proposes that deterioration occurs aggressively during the early years of psychosis, with relative stability subsequently. Thus, interventions that shorten the duration of untreated psychosis (DUP) and arrest early deterioration may have long-term benefits. AIMS To test the critical period hypothesis by determining whether outcome in non-affective psy...
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BACKGROUND Schizophrenia is associated with central (sagittal) midline reductions of the P300 cognitive event-related potential and topographic asymmetry of P300, with reduced left temporal voltage. This P300 asymmetry is, in turn, linked to tissue volume asymmetry in the posterior superior temporal gyrus. However, it is unknown whether P300 asymmetry is specific to schizophrenia and whether ce...
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ژورنال
عنوان ژورنال: Frontiers in Cellular Neuroscience
سال: 2021
ISSN: 1662-5102
DOI: 10.3389/fncel.2021.583351